'
Garden of Life Whole Food Vitamin C Code Raw Capsules
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.5
USERS' SCORE
Good
Based on 1 Review
8.4
Supplement Facts
Serving Size:  2 capsules
Amount Per Serving
%DV
Vitamin C (from culture of Saccharomyces cerevisiae)
500 mg
556%
Raw Organic Fruit & Vegetable Blend 
720 mg 
Raw Probiotic & Enzyme Blend
60 mg
+

Top Medical Research Studies

9
Vitamin C improves sleep apnea endothelial function
Antioxidant vitamin C improves endothelial function in obstructive sleep apnea.
Directly addresses vitamin C's effectiveness
We evaluated how vitamin C might improve endothelial function in patients with obstructive sleep apnea (OSA). In our study, we compared 10 individuals with untreated OSA to 10 matched control subjects without sleep issues. We measured how well blood vessels reacted to increased blood flow, known as flow-mediated dilation (FMD), using ultrasound before and after administering vitamin C.

Our findings revealed a significant difference: baseline FMD was lower in OSA patients compared to the control group. However, after an intravenous injection of vitamin C, the FMD in OSA patients improved dramatically, reaching levels similar to those seen in the healthy controls. Interestingly, vasoreactivity in the control subjects remained unchanged.

These results suggest that oxidative stress might be a key factor contributing to the endothelial dysfunction experienced by individuals with OSA. The positive response to vitamin C opens up exciting possibilities for exploring antioxidant treatments in managing cardiovascular issues related to OSA.
Read More
9
Vitamin C mitigates sleep apnea effects
Carotid body and cardiorespiratory alterations in intermittent hypoxia: the oxidative link.
Directly examines vitamin C benefits
We explored how vitamin C treatment affects individuals suffering from sleep apnea, particularly through the lens of intermittent hypoxia. In a study where male Sprague-Dawley rats were subjected to 5% oxygen levels, we observed that intermittent hypoxia led to notable changes in the body. These alterations included heightened carotid body responses to low oxygen, shifts in heart rate variability, and an increase in blood pressure.

The research specifically focused on the effects of ascorbic acid, or vitamin C, at a concentration of 1.25 g/L added to the drinking water of these rats over 21 days. What we found was quite promising: vitamin C treatment significantly reduced markers of oxidative stress in the plasma and carotid body. This antioxidant appeared to counteract the negative effects typically seen during intermittent hypoxia, including improved ventilatory responses to low oxygen levels and stabilization of heart rate and blood pressure.

Overall, our findings suggest that oxidative stress plays a crucial role in the heightened sensitivity and respiratory changes associated with sleep apnea. By mitigating these oxidative effects through vitamin C, we could potentially improve the quality of life for those affected by this condition.
Read More
8
Vitamin C may reduce sleep apnea
The Association Between Dietary Vitamin C and Sleep Disorders: A Cohort Study Based on UK Biobank.
Directly investigates vitamin C effect
We delved into an interesting question: can dietary vitamin C help alleviate sleep apnea? To explore this, we examined data from over 68,000 participants in the UK Biobank and focused on their dietary habits, particularly how much vitamin C they consumed. By using a detailed questionnaire to assess their intake and applying advanced statistical methods, we aimed to uncover any potential connections between vitamin C and sleep disorders, especially sleep apnea.

The results were quite revealing. Participants who consumed higher levels of vitamin C, particularly those in the top intake bracket (around 132.88 to 191.51 mg per day), showed a significant reduction in the risk of developing sleep disorders, including sleep apnea. Specifically, we found that this group had a 25% lower risk of sleep apnea compared to those with lower vitamin C intake.

What's even more encouraging is that this protective effect seemed particularly strong among men and those under 60 years old, suggesting that a sufficient intake of vitamin C could be a worthwhile strategy for preventing sleep apnea. Our findings highlight the importance of diet in managing sleep health and point to vitamin C as a valuable nutrient for those struggling with sleep issues.
Read More

Most Useful Reviews

7.5
Improved mood
I noticed no smell and found it easy to sleep with less stress, which has enhanced my mood. The size is good, and it's straightforward to use. The quality is commendable, the packaging is nice, and knowing it contains clean ingredients adds to my comfort. Importantly, this has helped me manage my sleep apnea effectively without any unpleasant taste.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.5
  • All Researches
9
Vitamin C mitigates sleep apnea effects
Carotid body and cardiorespiratory alterations in intermittent hypoxia: the oxidative link.
Directly examines vitamin C benefits
We explored how vitamin C treatment affects individuals suffering from sleep apnea, particularly through the lens of intermittent hypoxia. In a study where male Sprague-Dawley rats were subjected to 5% oxygen levels, we observed that intermittent hypoxia led to notable changes in the body. These alterations included heightened carotid body responses to low oxygen, shifts in heart rate variability, and an increase in blood pressure.

The research specifically focused on the effects of ascorbic acid, or vitamin C, at a concentration of 1.25 g/L added to the drinking water of these rats over 21 days. What we found was quite promising: vitamin C treatment significantly reduced markers of oxidative stress in the plasma and carotid body. This antioxidant appeared to counteract the negative effects typically seen during intermittent hypoxia, including improved ventilatory responses to low oxygen levels and stabilization of heart rate and blood pressure.

Overall, our findings suggest that oxidative stress plays a crucial role in the heightened sensitivity and respiratory changes associated with sleep apnea. By mitigating these oxidative effects through vitamin C, we could potentially improve the quality of life for those affected by this condition.
Read More
9
Vitamin C improves sleep apnea endothelial function
Antioxidant vitamin C improves endothelial function in obstructive sleep apnea.
Directly addresses vitamin C's effectiveness
We evaluated how vitamin C might improve endothelial function in patients with obstructive sleep apnea (OSA). In our study, we compared 10 individuals with untreated OSA to 10 matched control subjects without sleep issues. We measured how well blood vessels reacted to increased blood flow, known as flow-mediated dilation (FMD), using ultrasound before and after administering vitamin C.

Our findings revealed a significant difference: baseline FMD was lower in OSA patients compared to the control group. However, after an intravenous injection of vitamin C, the FMD in OSA patients improved dramatically, reaching levels similar to those seen in the healthy controls. Interestingly, vasoreactivity in the control subjects remained unchanged.

These results suggest that oxidative stress might be a key factor contributing to the endothelial dysfunction experienced by individuals with OSA. The positive response to vitamin C opens up exciting possibilities for exploring antioxidant treatments in managing cardiovascular issues related to OSA.
Read More
8
Vitamin C may reduce sleep apnea
The Association Between Dietary Vitamin C and Sleep Disorders: A Cohort Study Based on UK Biobank.
Directly investigates vitamin C effect
We delved into an interesting question: can dietary vitamin C help alleviate sleep apnea? To explore this, we examined data from over 68,000 participants in the UK Biobank and focused on their dietary habits, particularly how much vitamin C they consumed. By using a detailed questionnaire to assess their intake and applying advanced statistical methods, we aimed to uncover any potential connections between vitamin C and sleep disorders, especially sleep apnea.

The results were quite revealing. Participants who consumed higher levels of vitamin C, particularly those in the top intake bracket (around 132.88 to 191.51 mg per day), showed a significant reduction in the risk of developing sleep disorders, including sleep apnea. Specifically, we found that this group had a 25% lower risk of sleep apnea compared to those with lower vitamin C intake.

What's even more encouraging is that this protective effect seemed particularly strong among men and those under 60 years old, suggesting that a sufficient intake of vitamin C could be a worthwhile strategy for preventing sleep apnea. Our findings highlight the importance of diet in managing sleep health and point to vitamin C as a valuable nutrient for those struggling with sleep issues.
Read More
8
Vitamin C in sleep apnea treatment
Antioxidant therapies for obstructive sleep apnea: A systematic review and meta-analysis.
Combination therapy limits isolated effects
We explored how antioxidant therapies, including Vitamin C, can benefit individuals suffering from obstructive sleep apnea (OSA). A systematic review and meta-analysis looked into six studies involving various antioxidants, with the inclusion of Vitamin C among other treatments.

Our findings indicated that Vitamin C, alongside other antioxidants, contributed to improvements in several critical areas. We observed enhancements in endothelial function, which is essential for maintaining healthy blood flow. Additionally, the studies reported significant reductions in markers of oxidative stress and noteworthy improvements in sleep quality indicators.

While Vitamin C was part of the combination therapies assessed, it is essential to note that we cannot draw definitive conclusions about its standalone effectiveness for OSA. The overall positive results call for further exploration in future research to better understand the specific contributions of Vitamin C in treating this condition.
Read More
8
Vitamin C may enhance sleep apnea
Oxidative stress and obstructive sleep apnoea syndrome.
Combined treatment complicates findings
We explored the impact of vitamin C and antioxidant treatment on patients suffering from obstructive sleep apnea syndrome (OSAS). The study involved 20 male patients who first underwent continuous positive airway pressure (CPAP) therapy for two nights. Afterward, they took vitamin C (100 mg twice daily) and vitamin E (400 IU twice daily) for 45 days, followed by another sleep assessment through polysomnography (PSG).

Our findings revealed that oxidative stress seemed to play a significant role in sleep disturbances for OSAS patients. Treatment with vitamin C, alongside vitamin E and CPAP, led to improvements in sleep quality. Patients experienced a decrease in the number of apneic episodes and reported better overall sleep. Notably, there was a reduction in plasma lipid peroxidation and a restoration of reduced glutathione levels.

Even though the study combined various treatments, the data still suggests that antioxidants like vitamin C can bolster sleep quality for those with sleep apnea. Patients spent more time in restorative sleep stages and reported feeling less sleepy during the day.

Overall, while we should consider the combined effects of the treatments, this study highlights potential benefits of vitamin C in enhancing sleep for individuals affected by OSAS—supporting the idea that managing oxidative stress may improve sleep outcomes.
Read More

User Reviews

USERS' SCORE
Good
Based on 1 Review
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Improved mood
I noticed no smell and found it easy to sleep with less stress, which has enhanced my mood. The size is good, and it's straightforward to use. The quality is commendable, the packaging is nice, and knowing it contains clean ingredients adds to my comfort. Importantly, this has helped me manage my sleep apnea effectively without any unpleasant taste.
Read More
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